Two articles in one PNAS issue

Check out the latest issue of PNAS that contains two (2!) very interesting articles on mtDNA stability that we contributed to:

Awoyomi OF, Gorospe CM, Das B, Mishra P, Sharma S, Diachenko O, Nilsson AK, Tran P, Wanrooij PH^†, Chabes A^†.
RRM2B deficiency causes dATP and dGTP depletion through enhanced degradation and slower synthesis.

Forslund JME, Nguyen TVH, Parkash V, Berner A, Goffart S, Pohjoismäki JLO, Wanrooij PH, Johansson E, Wanrooij S.
The POLɣ Y951N patient mutation disrupts the switch between DNA synthesis and proofreading, triggering mitochondrial DNA instability.

Both were very interesting and fruitful collaborations – thanks to everyone involved!